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Gurbuxani, Sandeep
One or more keywords matched the following properties of Gurbuxani, Sandeep
PropertyValue
keywords Hematologic Malignancies
keywords Mouse models of Hematologic Malignancies
overview As an attending hematopathologist I am involved in diagnostic work up and follow up after therapy of patients diagnosed with hematologic malignancies including AML, ALL, MDS and MDS/MPN. I am interested in understanding the pathogenesis of hematopoietic tumors and how specific events required for leukemic transformation can be targeted for therapy. In addition, as part of collaborative research projects I have been involved in the analyses of mice in models of normal and malignant hematopoiesis.
One or more keywords matched the following items that are connected to Gurbuxani, Sandeep
Item TypeName
Concept Antibodies, Neoplasm
Concept Colonic Neoplasms
Concept Gastrointestinal Neoplasms
Concept Neoplasms, Multiple Primary
Concept Parathyroid Neoplasms
Concept Myeloproliferative Disorders
Concept Neoplasm Staging
Concept Spinal Neoplasms
Concept Biomarkers, Tumor
Concept Tumor Necrosis Factor-alpha
Concept Drug Resistance, Neoplasm
Concept Tumor Cells, Cultured
Concept Genes, Tumor Suppressor
Concept Neoplasms, Second Primary
Concept Lymphocytes, Tumor-Infiltrating
Concept Meningeal Neoplasms
Concept Neoplasm Recurrence, Local
Concept Neoplasms, Experimental
Concept Hematologic Neoplasms
Concept Cell Line, Tumor
Concept Genes, Neoplasm
Concept Neoplasm Proteins
Concept Neoplasms
Concept Neoplasm, Residual
Concept Myelodysplastic-Myeloproliferative Diseases
Academic Article Hsp27 negatively regulates cell death by interacting with cytochrome c.
Academic Article Expression of genes implicated in multidrug resistance in acute lymphoblastic leukemia in India.
Academic Article Significance of MDR1, MRP1, GSTpi and GSTmu mRNA expression in acute lymphoblastic leukemia in Indian patients.
Academic Article Identification of tumor-infiltrating macrophages as the killers of tumor cells after immunization in a rat model system.
Academic Article Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis.
Academic Article Mutations in GATA1 in both transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome.
Academic Article HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation.
Academic Article Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C.
Academic Article Heat shock proteins: endogenous modulators of apoptotic cell death.
Academic Article Chemosensitization by a non-apoptogenic heat shock protein 70-binding apoptosis-inducing factor mutant.
Academic Article Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome.
Academic Article Extranodal hairy cell leukemia presenting in the lumbar spine.
Academic Article What to do when you suspect gastrointestinal lymphoma: a pathologist's perspective.
Academic Article High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
Academic Article MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.
Academic Article Intracranial mucosa-associated lymphoid tissue (MALT) lymphoma.
Academic Article Beyond the 2008 World Health Organization classification: the role of the hematopathology laboratory in the diagnosis and management of acute lymphoblastic leukemia.
Academic Article Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Academic Article CHOP plus alemtuzumab can induce metabolic response by FDG-PET but has minimal long-term benefits: a case report and literature review.
Academic Article Overexpression of survivin initiates hematologic malignancies in vivo.
Academic Article Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells.
Academic Article Differential requirements for survivin in hematopoietic cell development.
Academic Article CHOP plus alemtuzumab can induce metabolic response by FDG-PET but has minimal long-term benefits: a case report and literature review.
Academic Article MDR1/P-glycoprotein in haematological neoplasms.
Academic Article TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Academic Article Stem cell factor expression in B cell malignancies is influenced by the niche.
Academic Article A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.
Academic Article AKT is a therapeutic target in myeloproliferative neoplasms.
Academic Article A new family with a germline ANKRD26 mutation and predisposition to myeloid malignancies.
Academic Article PLZF staining identifies peripheral T-cell lymphomas derived from innate-like T-cells with TRAV1-2-TRAJ33 TCR-a rearrangement.
Academic Article Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
Academic Article Overexpression and knockout of miR-126 both promote leukemogenesis.
Academic Article Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition.
Academic Article PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
Academic Article Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia.
Academic Article miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Academic Article Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.
Academic Article Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis.
Academic Article FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.
Academic Article The web of microRNA in B lymphoblastic leukemia.
Academic Article A Herald of Plasma Cell Myeloma: A Report of Malignant Plasma Cells Identified in Parathyroid Adenoma and a Review of Non-parathyroid Malignancies in Parathyroid Glands.
Academic Article Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial.
Academic Article Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks.
Academic Article Lymphoblastic leukemia following MDS or MDS/MPN: clinical evidence for stem cell origins of these disorders.
Academic Article Clinical outcomes of IDH2-mutated advanced-phase Ph-negative myeloproliferative neoplasms treated with enasidenib.
Academic Article CXCL4's "Gliful" subversion of BM in MPN.
Academic Article LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms.
Academic Article bcr3 PML-RARA: short fusion, small blasts!
Academic Article Loss of a 7q gene, CUX1, disrupts epigenetic-driven DNA repair and drives therapy-related myeloid neoplasms.
Academic Article Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
Academic Article Comparison of myeloid neoplasms with nonclassic 3q26.2/MECOM versus classic inv(3)/t(3;3) rearrangements reveals diverse clinicopathologic features, genetic profiles, and molecular mechanisms of MECOM activation.
Academic Article Therapy-related myeloid neoplasms with normal karyotype show distinct genomic and clinical characteristics compared to their counterparts with abnormal karyotype.
Academic Article Type I but Not Type II Calreticulin Mutations Activate the IRE1a/XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms.
Academic Article Elotuzumab and Weekly Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Without Transplant Intent: A Phase 2 Measurable Residual Disease-Adapted Study.
Academic Article IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms.
Academic Article EBV-positive inflammatory FDC/FRC tumor: no longer pseudo or sarcoma!
Academic Article The Times, They Are A-Changing: The Impact of Next-Generation Sequencing on Diagnosis, Classification, and Prognostication of Myeloid Malignancies With Focus on Myelodysplastic Syndrome, AML, and Germline Predisposition.
Academic Article Microbiota may affect the tumor type but not overall tumor development in two models of heritable cancer.
Academic Article Durable responses in acute lymphoblastic leukaemia with the use of FLT3 and IDH inhibitors.
Academic Article Acute lymphoblastic leukemia with myeloid mutations is a high-risk disease associated with clonal hematopoiesis.
Academic Article SETBP1 sets the stage.
Search Criteria
  • Myeloproliferative
  • neoplasms
  • MPN